Porcine cGAS-STING signaling induced autophagy inhibits STING downstream IFN and apoptosis

The innate immune DNA sensing cGAS-STING signaling pathway has been widely recognized for inducing interferons (IFNs) and subsequent antiviral state. In addition to IFN, the cGAS-STING pathway also elicits other cell autonomous immunity events including autophagy and apoptosis. However, the downstre...

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Detalles Bibliográficos
Autores principales: Xia, Nengwen, Zheng, Wanglong, Jiang, Sen, Cao, Qi, Luo, Jia, Zhang, Jiajia, Xu, Yulin, Sun, Shaohua, Zhang, Kaili, Chen, Nanhua, Meurens, François, Zhu, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608012/
https://www.ncbi.nlm.nih.gov/pubmed/36311807
http://dx.doi.org/10.3389/fimmu.2022.1021384

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