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Lipocalin 2 activates the NLRP3 inflammasome via LPS-induced NF-κB signaling and plays a role as a pro-inflammatory regulator in murine macrophages

Lipocalin 2 (LCN2) is highly expressed in several infectious and inflammatory disorders. However, the expression level and underlying mechanism of LCN2 in inflammatory bowel disease (IBD) are poorly understood. The current study used murine IBD models and LPS-activated macrophages to elucidate the r...

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Detalles Bibliográficos
Autores principales: Kim, Se Lim, Shin, Min Woo, Kim, Sang Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608086/
https://www.ncbi.nlm.nih.gov/pubmed/36263611
http://dx.doi.org/10.3892/mmr.2022.12875