Seizure-induced overexpression of NPY induces epileptic tolerance in a mouse model of spontaneous recurrent seizures

Epileptic seizures result in pronounced over-expression of neuropeptide Y (NPY). In vivo and in vitro studies revealed that NPY exerts potent anticonvulsive actions through presynaptic Y2 receptors by suppressing glutamate release from principal neurons. We now investigated whether seizure-induced o...

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Detalles Bibliográficos
Autores principales: Drexel, Meinrad, Sperk, Günther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608171/
https://www.ncbi.nlm.nih.gov/pubmed/36311021
http://dx.doi.org/10.3389/fnmol.2022.974784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608171/
https://www.ncbi.nlm.nih.gov/pubmed/36311021
http://dx.doi.org/10.3389/fnmol.2022.974784

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