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Seizure-induced overexpression of NPY induces epileptic tolerance in a mouse model of spontaneous recurrent seizures
Epileptic seizures result in pronounced over-expression of neuropeptide Y (NPY). In vivo and in vitro studies revealed that NPY exerts potent anticonvulsive actions through presynaptic Y2 receptors by suppressing glutamate release from principal neurons. We now investigated whether seizure-induced o...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608171/ https://www.ncbi.nlm.nih.gov/pubmed/36311021 http://dx.doi.org/10.3389/fnmol.2022.974784 |