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Glutamate NMDA Receptor Antagonists with Relevance to Schizophrenia: A Review of Zebrafish Behavioral Studies

Schizophrenia pathophysiology is associated with hypofunction of glutamate NMDA receptors (NMDAR) in GABAergic interneurons and dopaminergic hyperactivation in subcortical brain areas. The administration of NMDAR antagonists is used as an animal model that replicates behavioral phenotypes relevant t...

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Detalles Bibliográficos
Autores principales: Benvenutti, Radharani, Gallas-Lopes, Matheus, Marcon, Matheus, Reschke, Cristina R., Herrmann, Ana Paula, Piato, Angelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608229/
https://www.ncbi.nlm.nih.gov/pubmed/33588731
http://dx.doi.org/10.2174/1570159X19666210215121428