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Acid-Promoted Redox-Annulation toward 1,2-Disubstituted-5,6-dihydropyrrolo[2,1-α]isoquinolines: Synthesis of the Lamellarin Core

[Image: see text] An efficient synthesis of a variety of 1,2-disubstituted-5,6-dihydropyrrolo[2,1-α]isoquinoline derivatives via an acid-promoted cyclization reaction between 1,2,3,4-tetrahydroisoquinoline (THIQ) and substituted α,β-unsaturated aldehyde derivatives is reported. This cycloaddition al...

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Detalles Bibliográficos
Autores principales: Hou, Guo-Quan, Zhao, Wenyan, Deng, Changjiang, Dong, Chunping, Wang, Cheli, Liu, Li, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608416/
https://www.ncbi.nlm.nih.gov/pubmed/36312359
http://dx.doi.org/10.1021/acsomega.2c01941