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Tumor MHC class I expression alters cancer-associated myelopoiesis driven by host NK cells

Downregulation of MHC class I (MHCI) molecules on tumor cells is recognized as a resistance mechanism of cancer immunotherapy. Given that MHCI molecules are potent regulators of immune responses, we postulated that the expression of MHCI by tumor cells influences systemic immune responses. According...

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Detalles Bibliográficos
Autores principales: Neo, Shi Yong, Jing, Xu, Tong, Le, Tong, Dongmei, Gao, Juan, Chen, Ziqing, De Los Santos, Mireia Cruz, Burduli, Nutsa, De Souza Ferreira, Sabrina, Wagner, Arnika Kathleen, Alici, Evren, Rolny, Charlotte, Cao, Yihai, Lundqvist, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608525/
https://www.ncbi.nlm.nih.gov/pubmed/36283735
http://dx.doi.org/10.1136/jitc-2022-005308