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Determination of Bupropion and Its Impurities via a Chaotropic Chromatography Method Following Analytical Quality-by-Design Principles for Method Development

A novel chaotropic chromatography method for the quantitative determination of bupropion and its impurities, following analytical quality-by-design (AQbD) principles, is presented. The analytical target profile (ATP) was defined on the basis of the efficient separation and reliable determination of...

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Detalles Bibliográficos
Autores principales: Gkountanas, Kostas, Malenović, Anđelija, Dotsikas, Yannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608554/
https://www.ncbi.nlm.nih.gov/pubmed/36297308
http://dx.doi.org/10.3390/ph15101196