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Therapeutic Drug Monitoring of Quinidine in Pediatric Patients with KCNT1 Genetic Variants

Quinidine (QND) is an old antimalarial drug that was used in the early 20th century as an antiarrhythmic agent. Currently, QND is receiving attention for its use in epilepsy of infancy with migrating focal seizures (EIMFS) due to potassium sodium-activated channel subfamily T member 1 (KCNT1) geneti...

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Detalles Bibliográficos
Autores principales: Ferretti, Alessandro, Simeoli, Raffaele, Cairoli, Sara, Pietrafusa, Nicola, Trivisano, Marina, Dionisi Vici, Carlo, Specchio, Nicola, Goffredo, Bianca Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608568/
https://www.ncbi.nlm.nih.gov/pubmed/36297665
http://dx.doi.org/10.3390/pharmaceutics14102230