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Therapeutic Drug Monitoring of Quinidine in Pediatric Patients with KCNT1 Genetic Variants
Quinidine (QND) is an old antimalarial drug that was used in the early 20th century as an antiarrhythmic agent. Currently, QND is receiving attention for its use in epilepsy of infancy with migrating focal seizures (EIMFS) due to potassium sodium-activated channel subfamily T member 1 (KCNT1) geneti...
Autores principales: | Ferretti, Alessandro, Simeoli, Raffaele, Cairoli, Sara, Pietrafusa, Nicola, Trivisano, Marina, Dionisi Vici, Carlo, Specchio, Nicola, Goffredo, Bianca Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608568/ https://www.ncbi.nlm.nih.gov/pubmed/36297665 http://dx.doi.org/10.3390/pharmaceutics14102230 |
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