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Cardiac Sodium/Hydrogen Exchanger (NHE11) as a Novel Potential Target for SGLT2i in Heart Failure: A Preliminary Study

Despite the reduction of cardiovascular events, including the risk of death, associated with sodium/glucose cotransporter 2 inhibitors (SGLT2i), their basic action remains unclear. Sodium/hydrogen exchanger (NHE) has been proposed as the mechanism of action, but there are controversies related to it...

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Detalles Bibliográficos
Autores principales: Pérez-Carrillo, Lorena, Aragón-Herrera, Alana, Giménez-Escamilla, Isaac, Delgado-Arija, Marta, García-Manzanares, María, Anido-Varela, Laura, Lago, Francisca, Martínez-Dolz, Luis, Portolés, Manuel, Tarazón, Estefanía, Roselló-Lletí, Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608584/
https://www.ncbi.nlm.nih.gov/pubmed/36297433
http://dx.doi.org/10.3390/pharmaceutics14101996