Intermedin Alleviates Vascular Calcification in CKD through Sirtuin 3-Mediated Inhibition of Mitochondrial Oxidative Stress

Vascular calcification (VC) is a common pathophysiological process of chronic kidney disease (CKD). Sirtuin 3 (Sirt3), a major NAD(+)-dependent protein deacetylase predominantly in mitochondria, is involved in the pathogenesis of VC. We previously reported that intermedin (IMD) could protect against...

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Detalles Bibliográficos
Autores principales: Liu, Shi-Meng, Zhang, Ya-Rong, Chen, Yao, Ji, Deng-Ren, Zhao, Jie, Fu, Su, Jia, Mo-Zhi, Yu, Yan-Rong, Tang, Chao-Shu, Huang, Wei, Zhou, Ye-Bo, Qi, Yong-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608591/
https://www.ncbi.nlm.nih.gov/pubmed/36297336
http://dx.doi.org/10.3390/ph15101224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608591/
https://www.ncbi.nlm.nih.gov/pubmed/36297336
http://dx.doi.org/10.3390/ph15101224

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