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Metformin alleviates irradiation-induced intestinal injury by activation of FXR in intestinal epithelia

Abdominal irradiation (IR) destroys the intestinal mucosal barrier, leading to severe intestinal infection. There is an urgent need to find safe and effective treatments to reduce IR-induced intestinal injury. In this study, we reported that metformin protected mice from abdominal IR-induced intesti...

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Detalles Bibliográficos
Autores principales: Yang, Jing-Yu, Liu, Meng-Jie, Lv, Lin, Guo, Jin-Rong, He, Kai-Yue, Zhang, Hong, Wang, Ke-Ke, Cui, Cui-Yun, Yan, Bei-Zhan, Du, Dan-Dan, Wang, Jin-Hua, Ding, Qiang, Liu, Guo-Long, Xu, Zhi-Xiang, Jian, Yong-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608595/
https://www.ncbi.nlm.nih.gov/pubmed/36312920
http://dx.doi.org/10.3389/fmicb.2022.932294