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Metformin alleviates irradiation-induced intestinal injury by activation of FXR in intestinal epithelia
Abdominal irradiation (IR) destroys the intestinal mucosal barrier, leading to severe intestinal infection. There is an urgent need to find safe and effective treatments to reduce IR-induced intestinal injury. In this study, we reported that metformin protected mice from abdominal IR-induced intesti...
Autores principales: | Yang, Jing-Yu, Liu, Meng-Jie, Lv, Lin, Guo, Jin-Rong, He, Kai-Yue, Zhang, Hong, Wang, Ke-Ke, Cui, Cui-Yun, Yan, Bei-Zhan, Du, Dan-Dan, Wang, Jin-Hua, Ding, Qiang, Liu, Guo-Long, Xu, Zhi-Xiang, Jian, Yong-Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608595/ https://www.ncbi.nlm.nih.gov/pubmed/36312920 http://dx.doi.org/10.3389/fmicb.2022.932294 |
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