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Nano-Dry-Melting: A Novel Technology for Manufacturing of Pharmaceutical Amorphous Solid Dispersions

Amorphous solid dispersions (ASD) are one of the most prominent formulation approaches to overcome bioavailability issues that are often presented by new poorly soluble drug candidates. State-of-the art manufacturing techniques include hot melt extrusion and solvent-based methods like spray drying....

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Detalles Bibliográficos
Autores principales: Hermeling, Malin, Nueboldt, Christoph, Heumann, Roman, Hoheisel, Werner, Breitkreutz, Joerg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608596/
https://www.ncbi.nlm.nih.gov/pubmed/36297580
http://dx.doi.org/10.3390/pharmaceutics14102145