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Synthesis and Identification of New N,N-Disubstituted Thiourea, and Thiazolidinone Scaffolds Based on Quinolone Moiety as Urease Inhibitor

Synthesis of thiazolidinone based on quinolone moiety was established starting from 4-hydroxyquinol-2-ones. The strategy started with the reaction of ethyl bromoacetate with 4-hydroxyquinoline to give the corresponding ethyl oxoquinolinyl acetates, which reacted with hydrazine hydrate to afford the...

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Detalles Bibliográficos
Autores principales: Elshaier, Yaseen A. M. M., Aly, Ashraf A., Abdel-Aziz, Mohamed, Fathy, Hazem M., Brown, Alan B., Bräse, Stefan, Ramadan, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608620/
https://www.ncbi.nlm.nih.gov/pubmed/36296723
http://dx.doi.org/10.3390/molecules27207126