HLA-B*27 Heavy Chain Homo-Oligomers Promote the Cytotoxicity of NK Cells via Activation of PI3K/AKT Signaling

Background and Objectives: Ankylosing spondylitis (AS) is a chronic inflammatory disease and is highly linked with the expression of the human leukocytic antigen-B*27 (HLA-B*27) genotype. HLA-B*27 heavy chain (B*27-HC) has an innate characteristic to slowly fold, resulting in the accumulation of the...

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Detalles Bibliográficos
Autores principales: Yu, Hui-Chun, Huang, Kuang-Yung, Lu, Ming-Chi, Huang Tseng, Hsien-Yu, Liu, Su-Qin, Lai, Ning-Sheng, Huang, Hsien-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608704/
https://www.ncbi.nlm.nih.gov/pubmed/36295572
http://dx.doi.org/10.3390/medicina58101411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608704/
https://www.ncbi.nlm.nih.gov/pubmed/36295572
http://dx.doi.org/10.3390/medicina58101411

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