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Fast Absorbent and Highly Bioorthogonal Hydrogels Developed by IEDDA Click Reaction for Drug Delivery Application

In this work, we engineered highly biocompatible and fast absorbent injectable hydrogels derived from norbornene (Nb)-functionalized hyaluronic acid (HA-Nb) and a water-soluble cross-linker possessing tetrazine (Tz) functional groups on both ends of polyethylene glycol (PEG-DTz). The by-product (nit...

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Detalles Bibliográficos
Autores principales: Joo, Soo-Bin, Gulfam, Muhammad, Jo, Sung-Han, Jo, Yi-Jun, Vu, Trung Thang, Park, Sang-Hyug, Gal, Yeong-Soon, Lim, Kwon Taek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608709/
https://www.ncbi.nlm.nih.gov/pubmed/36295196
http://dx.doi.org/10.3390/ma15207128