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NIL10: A New IL10-Receptor Binding Nanoparticle That Induces Cardiac Protection in Mice and Pigs Subjected to Acute Myocardial Infarction through STAT3/NF-κB Activation

(1) Background: Early response after acute myocardial infarction (AMI) prevents extensive cardiac necrosis, in which inflammation resolution, including expression of anti-inflammatory interleukin-10 (IL-10), may play a key role. (2) Methods: We synthesized NIL10, a micelle-based nanoparticle, to tar...

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Detalles Bibliográficos
Autores principales: Tesoro, Laura, Hernández, Ignacio, Ramírez-Carracedo, Rafael, Díez-Mata, Javier, Alcharani, Nunzio, Jiménez-Guirado, Beatriz, Ovejero-Paredes, Karina, Filice, Marco, Zamorano, Jose Luis, Saura, Marta, Zaragoza, Carlos, Botana, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608724/
https://www.ncbi.nlm.nih.gov/pubmed/36297479
http://dx.doi.org/10.3390/pharmaceutics14102044