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NIL10: A New IL10-Receptor Binding Nanoparticle That Induces Cardiac Protection in Mice and Pigs Subjected to Acute Myocardial Infarction through STAT3/NF-κB Activation
(1) Background: Early response after acute myocardial infarction (AMI) prevents extensive cardiac necrosis, in which inflammation resolution, including expression of anti-inflammatory interleukin-10 (IL-10), may play a key role. (2) Methods: We synthesized NIL10, a micelle-based nanoparticle, to tar...
Autores principales: | Tesoro, Laura, Hernández, Ignacio, Ramírez-Carracedo, Rafael, Díez-Mata, Javier, Alcharani, Nunzio, Jiménez-Guirado, Beatriz, Ovejero-Paredes, Karina, Filice, Marco, Zamorano, Jose Luis, Saura, Marta, Zaragoza, Carlos, Botana, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608724/ https://www.ncbi.nlm.nih.gov/pubmed/36297479 http://dx.doi.org/10.3390/pharmaceutics14102044 |
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