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Altered transcription factor targeting is associated with differential peripheral blood mononuclear cell proportions in sarcoidosis
INTRODUCTION: In sarcoidosis, peripheral lymphopenia and anergy have been associated with increased inflammation and maladaptive immune activity, likely promoting development of chronic and progressive disease. However, the molecular mechanisms that lead to reduced lymphocyte proportions, particular...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608777/ https://www.ncbi.nlm.nih.gov/pubmed/36311769 http://dx.doi.org/10.3389/fimmu.2022.848759 |