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Altered transcription factor targeting is associated with differential peripheral blood mononuclear cell proportions in sarcoidosis

INTRODUCTION: In sarcoidosis, peripheral lymphopenia and anergy have been associated with increased inflammation and maladaptive immune activity, likely promoting development of chronic and progressive disease. However, the molecular mechanisms that lead to reduced lymphocyte proportions, particular...

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Detalles Bibliográficos
Autores principales: Ascoli, Christian, Schott, Cody A., Huang, Yue, Turturice, Benjamin A., Wang, Wangfei, Ecanow, Naomi, Sweiss, Nadera J., Perkins, David L., Finn, Patricia W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608777/
https://www.ncbi.nlm.nih.gov/pubmed/36311769
http://dx.doi.org/10.3389/fimmu.2022.848759