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Combination therapy with budesonide and N-acetylcysteine ameliorates LPS-induced ALI by attenuating neutrophil recruitment through the miR-196b-5p/Socs3 molecular axis

BACKGROUND: Neutrophil infiltration accelerates the inflammatory response and is highly correlated to the development of acute lung injury (ALI). Budesonide (BUD) and N-acetylcysteine (NAC) both inhibit the inflammatory response to alleviate ALI, so we further investigated whether their combination...

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Detalles Bibliográficos
Autores principales: Li, Yang, Yu, Huimin, Lv, Meifen, Li, Qiaofen, Zou, Kaiwen, Lv, Shaokun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608916/
https://www.ncbi.nlm.nih.gov/pubmed/36289489
http://dx.doi.org/10.1186/s12890-022-02185-7