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Biochemical characterization of a cyanobactin arginine-N-prenylase from the autumnalamide biosynthetic pathway

Cyanobactins are linear and cyclic post-translationally modified peptides. Here we show that the prenyl-d-Arg-containing autumnalamide A is a member of the cyanobactin family. Biochemical assays demonstrate that the AutF prenyltransferase targets the guanidinium moiety in arginine and homoarginine a...

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Detalles Bibliográficos
Autores principales: Clemente, Claudia, Johnson, Nicholas, Ouyang, Xiaodan, Popin, Rafael V., Dall'Angelo, Sergio, Wahlsten, Matti, Jokela, Jouni, Colombano, Alessandro, Nardone, Brunello, Fewer, David P., Houssen, Wael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609003/
https://www.ncbi.nlm.nih.gov/pubmed/36193595
http://dx.doi.org/10.1039/d2cc01799g