Novel triple mutant of an extremophilic glycosyl hydrolase enables the rapid synthesis of thioglycosides

In order to expand the toolbox of enzymes available for thioglycoside synthesis, we describe here the first example of an extremophilic glycosyl hydrolase from Halothermothrix orenii (HorGH1) engineered towards thioglycosynthase activity with a novel combination of mutations. Using the triple mutant...

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Detalles Bibliográficos
Autores principales: Pillet, Lauriane, Lim, David, Almulhim, Nourah, Benítez-Mateos, Ana I., Paradisi, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609006/
https://www.ncbi.nlm.nih.gov/pubmed/36226508
http://dx.doi.org/10.1039/d2cc04660a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609006/
https://www.ncbi.nlm.nih.gov/pubmed/36226508
http://dx.doi.org/10.1039/d2cc04660a

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