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Novel triple mutant of an extremophilic glycosyl hydrolase enables the rapid synthesis of thioglycosides
In order to expand the toolbox of enzymes available for thioglycoside synthesis, we describe here the first example of an extremophilic glycosyl hydrolase from Halothermothrix orenii (HorGH1) engineered towards thioglycosynthase activity with a novel combination of mutations. Using the triple mutant...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609006/ https://www.ncbi.nlm.nih.gov/pubmed/36226508 http://dx.doi.org/10.1039/d2cc04660a |