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Evaluation of Hydroxyethyl Cellulose Grades as the Main Matrix Former to Produce 3D-Printed Controlled-Release Dosage Forms

Diclofenac sodium tablets were successfully prepared via hot-melt extrusion (HME) and fused deposition modeling (FDM), using different molecular-weight (Mw) grades of hydroxyethyl cellulose (HEC) as the main excipient. Hydroxypropyl cellulose (HPC) was added to facilitate HME and to produce drug-loa...

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Detalles Bibliográficos
Autores principales: Hartzke, David, Pössl, Axel, Schlupp, Peggy, Runkel, Frank E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609046/
https://www.ncbi.nlm.nih.gov/pubmed/36297538
http://dx.doi.org/10.3390/pharmaceutics14102103