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Effect of N-Methyl-pyrrolidone (NMP) on the Equilibrium Solubility of Meloxicam in Aqueous Media: Correlation, Dissolution Thermodynamics, and Preferential Solvation

[Image: see text] Meloxicam is an analgesic and anti-inflammatory drug widely prescribed in current therapeutics that exhibits very low solubility in water. Thus, this physicochemical property has been studied in N-methyl-pyrrolidone (NMP)–aqueous mixtures at several temperatures to expand the solub...

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Detalles Bibliográficos
Autores principales: Tinjacá, Darío A., Martínez, Fleming, Almanza, Ovidio A., Jouyban, Abolghasem, Acree, William E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609070/
https://www.ncbi.nlm.nih.gov/pubmed/36312332
http://dx.doi.org/10.1021/acsomega.2c05189