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Revisiting the Dissolution of Praziquantel in Biorelevant Media and the Impact of Digestion of Milk on Drug Dissolution

Praziquantel is a poorly water-soluble drug used to treat parasitic infections. Previous studies have suggested that its rate and extent of dissolution in milk and biorelevant media are slow and limited compared to dissolution in the pharmacopoeial-recommended medium, despite being reported as displ...

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Detalles Bibliográficos
Autores principales: Eason, Thomas, Ramirez, Gisela, Clulow, Andrew J., Salim, Malinda, Boyd, Ben J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609124/
https://www.ncbi.nlm.nih.gov/pubmed/36297662
http://dx.doi.org/10.3390/pharmaceutics14102228