Cargando…

Revisiting the Dissolution of Praziquantel in Biorelevant Media and the Impact of Digestion of Milk on Drug Dissolution

Praziquantel is a poorly water-soluble drug used to treat parasitic infections. Previous studies have suggested that its rate and extent of dissolution in milk and biorelevant media are slow and limited compared to dissolution in the pharmacopoeial-recommended medium, despite being reported as displ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Eason, Thomas, Ramirez, Gisela, Clulow, Andrew J., Salim, Malinda, Boyd, Ben J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609124/ https://www.ncbi.nlm.nih.gov/pubmed/36297662 http://dx.doi.org/10.3390/pharmaceutics14102228

Ejemplares similares

Intrinsic Dissolution Rate Profiling of Poorly Water-Soluble Compounds in Biorelevant Dissolution Media
por: Teleki, Alexandra, et al.
Publicado: (2020)

Revisiting dispersible milk-drug tablets as a solid lipid formulation in the context of digestion
por: Binte Abu Bakar, Syaza Y., et al.
Publicado: (2019)

Small-volume in vitro lipid digestion measurements for assessing drug dissolution in lipid-based formulations using SAXS
por: Khan, Nafia F., et al.
Publicado: (2022)

The impact of digestion is essential to the understanding of milk as a drug delivery system for poorly water soluble drugs
por: Boyd, Ben J., et al.
Publicado: (2018)

Implications of the Digestion of Milk-Based Formulations for the Solubilization of Lopinavir/Ritonavir in a Combination Therapy
por: Salim, Malinda, et al.
Publicado: (2023)

Optimization of Dissolution Compartments in a Biorelevant Dissolution Apparatus Golem v2, Supported by Multivariate Analysis
por: Stupák, Ivan, et al.
Publicado: (2017)

Development and Validation of Discriminating and Biorelevant Dissolution Test for Lornoxicam Tablets
por: Anumolu, P. D., et al.
Publicado: (2015)

Dissolution Profile of Mefenamic Acid Solid Dosage Forms in Two Compendial and Biorelevant (FaSSIF) Media
por: Nurhikmah, Wilda, et al.
Publicado: (2016)

Correlating Digestion-Driven Self-Assembly in Milk and Infant Formulas with Changes in Lipid Composition
por: Pham, Anna C., et al.
Publicado: (2020)

The Effect of Biorelevant Hydrodynamic Conditions on Drug Dissolution from Extended-Release Tablets in the Dynamic Colon Model
por: O’Farrell, Connor, et al.
Publicado: (2022)

Use of PBPK Modeling To Evaluate the Performance of DissolvIt, a Biorelevant Dissolution Assay for Orally Inhaled Drug Products
por: Hassoun, Mireille, et al.
Publicado: (2019)

Novel biorelevant dissolution medium as a prognostic tool for polysaccharide-based colon-targeted drug delivery system
por: Yadav, Ankit Kumar, et al.
Publicado: (2017)

The Effect of the Particle Size Reduction on the Biorelevant Solubility and Dissolution of Poorly Soluble Drugs with Different Acid-Base Character
por: Csicsák, Dóra, et al.
Publicado: (2023)

Role of Biorelevant Dissolution Media in the Selection of Optimal Salt Forms of Oral Drugs: Maximizing the Gastrointestinal Solubility and in Vitro Activity of the Antimicrobial Molecule, Clofazimine
por: Bannigan, Pauric, et al.
Publicado: (2017)

Dissolution of Pentoxifylline from Extended Release Formulations. Researches Concerning Development of a Biorelevant Test
por: Ionica, Georgeta, et al.
Publicado: (2009)

Low-Frequency Raman Scattering Spectroscopy as an Accessible Approach to Understand Drug Solubilization in Milk-Based Formulations during Digestion
por: Salim, Malinda, et al.
Publicado: (2020)

Lipid Compositions in Infant Formulas Affect the Solubilization of Antimalarial Drugs Artefenomel (OZ439) and Ferroquine during Digestion
por: Salim, Malinda, et al.
Publicado: (2020)

Solid-State Behavior and Solubilization of Flash Nanoprecipitated Clofazimine Particles during the Dispersion and Digestion of Milk-Based Formulations
por: Salim, Malinda, et al.
Publicado: (2019)

Application of Low-Frequency Raman Scattering Spectroscopy to Probe in Situ Drug Solubilization in Milk during Digestion
por: Salim, Malinda, et al.
Publicado: (2019)

Exploration of Neusilin(®) US2 as an Acceptable Filler in HPMC Matrix Systems—Comparison of Pharmacopoeial and Dynamic Biorelevant Dissolution Study
por: Bílik, Tomáš, et al.
Publicado: (2022)

Impact of pasteurization on the self-assembly of human milk lipids during digestion
por: Binte Abu Bakar, Syaza Y., et al.
Publicado: (2022)

Retraction of the dissolution front in natural porous media
por: Yang, Y., et al.
Publicado: (2018)

Ground Calcium Carbonate as a Low Cost and Biosafety Excipient for Solubility and Dissolution Improvement of Praziquantel
por: Borrego-Sánchez, Ana, et al.
Publicado: (2019)

A study of the heat-mediated phase transformations of praziquantel hydrates. Evaluation of their impact on the dissolution rate
por: Salazar-Rojas, Duvernis, et al.
Publicado: (2022)

Dissolution
Publicado: (1885)

Dissolution
Publicado: (1881)

Impact of Ferroquine on the Solubilization of Artefenomel (OZ439) during in Vitro Lipolysis in Milk and Implications for Oral Combination Therapy for Malaria
por: Salim, Malinda, et al.
Publicado: (2019)

Revisiting the Dissolution of Cellulose in NaOH as “Seen” by X-rays
por: Martin-Bertelsen, Birte, et al.
Publicado: (2020)

A Rational Design of a Biphasic Dissolution Setup—Modelling of Biorelevant Kinetics for a Ritonavir Hot-Melt Extruded Amorphous Solid Dispersion
por: Denninger, Alexander, et al.
Publicado: (2020)

Characterization of Affitin proteolytic digestion in biorelevant media and improvement of their stabilities via protein engineering
por: Loussouarn, Aurélie, et al.
Publicado: (2020)

Surface Dissolution UV Imaging for Investigation of Dissolution of Poorly Soluble Drugs and Their Amorphous Formulation
por: Long, Chiau Ming, et al.
Publicado: (2019)

Selection of In Vivo Predictive Dissolution Media Using Drug Substance and Physiological Properties
por: Mudie, Deanna M., et al.
Publicado: (2020)

Mental Dissolution
por: Savage, G. H.
Publicado: (1900)

Kinetic study of uranium residue dissolution in ammonium carbonate media
por: Kweto, B., et al.
Publicado: (2014)

Ego-Dissolution and Psychedelics: Validation of the Ego-Dissolution Inventory (EDI)
por: Nour, Matthew M., et al.
Publicado: (2016)

Reductive dissolution of pyrite by methanogenic archaea
por: Payne, Devon, et al.
Publicado: (2021)

Nanosizing of drugs: Effect on dissolution rate
por: Dizaj, S. Maleki, et al.
Publicado: (2015)

Sustained absorption of delamanid from lipid-based formulations as a path to reduced frequency of administration
por: Ramirez, Gisela, et al.
Publicado: (2020)

The influence of lipid digestion on the fate of orally administered drug delivery vehicles
por: Boyd, Ben J., et al.
Publicado: (2021)

Dissolution Behaviour of Metal-Oxide Nanomaterials in Various Biological Media
por: Avramescu, Mary-Luyza, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_n7h4pc8kjsi795j3j6v2jomfp7