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Efficient Delivery of P3H4 siRNA and Chlorin e6 by cRGDfK-Installed Polyarginine Nanoparticles for Tumor-Targeting Therapy of Bladder Cancer

Purpose: Prolyl 3-hydroxylase family member 4 (P3H4) is a potent prognostic oncogene in bladder cancer (BC), and the inhibition of P3H4 suppresses BC tumor growth. This study aimed to evaluate the efficiency of P3H4 inhibition for BC tumor therapy via tumor-targeting nanoparticles. Methods and resul...

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Detalles Bibliográficos
Autores principales: Hao, Lin, Shi, Zhenduo, Dong, Yang, Chen, Jiangang, Pang, Kun, He, Houguang, Zhang, Shaoqi, Wu, Wei, Zhang, Qianjin, Han, Conghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609145/
https://www.ncbi.nlm.nih.gov/pubmed/36297587
http://dx.doi.org/10.3390/pharmaceutics14102149