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Isoniazid Linked to Sulfonate Esters via Hydrazone Functionality: Design, Synthesis, and Evaluation of Antitubercular Activity

Isoniazid (INH) is one of the key molecules employed in the treatment of tuberculosis (TB), the most deadly infectious disease worldwide. However, the efficacy of this cornerstone drug has seriously decreased due to emerging INH-resistant strains of Mycobacterium tuberculosis (Mtb). In the present s...

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Detalles Bibliográficos
Autores principales: Koçak Aslan, Ebru, Han, Muhammed İhsan, Krishna, Vagolu Siva, Tamhaev, Rasoul, Dengiz, Cagatay, Doğan, Şengül Dilem, Lherbet, Christian, Mourey, Lionel, Tønjum, Tone, Gündüz, Miyase Gözde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609273/
https://www.ncbi.nlm.nih.gov/pubmed/36297413
http://dx.doi.org/10.3390/ph15101301