G-Quadruplex Aptamer-Ligand Characterization

In this work we explore the structure of a G-rich DNA aptamer termed AT11-L2 (TGGTGGTGGTTGTTGTTGGTGGTGGTGGT; derivative of AT11) by evaluating the formation and stability of G-quadruplex (G4) conformation under different experimental conditions such as KCl concentration, temperature, and upon bindin...

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Detalles Bibliográficos
Autores principales: Moreira, David, Leitão, Daniela, Lopes-Nunes, Jéssica, Santos, Tiago, Figueiredo, Joana, Miranda, André, Alexandre, Daniela, Tomaz, Cândida, Mergny, Jean-Louis, Cruz, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609330/
https://www.ncbi.nlm.nih.gov/pubmed/36296374
http://dx.doi.org/10.3390/molecules27206781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609330/
https://www.ncbi.nlm.nih.gov/pubmed/36296374
http://dx.doi.org/10.3390/molecules27206781

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