Altered mannose metabolism in chronic stress and depression is rapidly reversed by vitamin B12

GDP-Mannose Pyrophosphorylase B (GMPPB) is a key enzyme for glycosylation. Previous studies suggested a dysregulation of GMPBB and mannose in depression. Evidence, however, was sporadic and interventions to reverse these changes are unknown. Here, we show that GMPPB protein, but not RNA abundance is...

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Detalles Bibliográficos
Autores principales: Franzka, Patricia, Turecki, Gustavo, Cubillos, Susana, Kentache, Takfarinas, Steiner, Johann, Walter, Martin, Hübner, Christian A., Engmann, Olivia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Nutrition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609420/
https://www.ncbi.nlm.nih.gov/pubmed/36313076
http://dx.doi.org/10.3389/fnut.2022.981511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609420/
https://www.ncbi.nlm.nih.gov/pubmed/36313076
http://dx.doi.org/10.3389/fnut.2022.981511

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