Enhanced Production of ECM Proteins for Pharmaceutical Applications Using Mammalian Cells and Sodium Heparin Supplementation

The yields of soluble ECM proteins recombinantly produced with mammalian cells can be significantly enhanced by exploiting the stabilizing properties of heparin. Here, we propose a simple and straightforward scalable protocol for the mammalian cell production of ECM proteins with affinity for hepari...

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Detalles Bibliográficos
Autores principales: Garcia-Pardo, Javier, Montané, Sergi, Avilés, Francesc Xavier, Tanco, Sebastian, Lorenzo, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609459/
https://www.ncbi.nlm.nih.gov/pubmed/36297573
http://dx.doi.org/10.3390/pharmaceutics14102138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609459/
https://www.ncbi.nlm.nih.gov/pubmed/36297573
http://dx.doi.org/10.3390/pharmaceutics14102138

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