Chromosomal instability (CIN) in HAP1 cell lines revealed by multiplex fluorescence in situ hybridisation (M-FISH)

BACKGROUND: HAP1, a near-haploid human leukemic cancer cell line is often used in combination with CRISPR-Cas9 gene editing technology for genetic screens. HAP1 carries the Philadelphia chromosome (Ph) and an additional ~ 30 Mb fragment of chromosome 15 inserted into chromosome 19. The potential use...

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Detalles Bibliográficos
Autores principales: Banerjee, Ruby, Sotero-Caio, Cibele G., Fu, Beiyuan, Yang, Fengtang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609465/
https://www.ncbi.nlm.nih.gov/pubmed/36289492
http://dx.doi.org/10.1186/s13039-022-00625-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609465/
https://www.ncbi.nlm.nih.gov/pubmed/36289492
http://dx.doi.org/10.1186/s13039-022-00625-x

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