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Adeno-associated virus-based caveolin-1 delivery via different routes for the prevention of cholesterol gallstone formation
BACKGROUND: Hepatic caveolin-1 (CAV1) is reduced in cholesterol gallstone disease (CGD). Mice with CAV1 deficiency were prone to develop CGD. However, it remains unknown whether restored hepatic CAV1 expression prevents the development of CGD. METHODS: C57BL/6 mice were injected with adeno-associate...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609467/ https://www.ncbi.nlm.nih.gov/pubmed/36303150 http://dx.doi.org/10.1186/s12944-022-01718-7 |