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Adeno-associated virus-based caveolin-1 delivery via different routes for the prevention of cholesterol gallstone formation

BACKGROUND: Hepatic caveolin-1 (CAV1) is reduced in cholesterol gallstone disease (CGD). Mice with CAV1 deficiency were prone to develop CGD. However, it remains unknown whether restored hepatic CAV1 expression prevents the development of CGD. METHODS: C57BL/6 mice were injected with adeno-associate...

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Detalles Bibliográficos
Autores principales: Li, Sha, Chen, Hongtan, Jiang, Xin, Hu, Fengling, Li, Yiqiao, Xu, Guoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609467/
https://www.ncbi.nlm.nih.gov/pubmed/36303150
http://dx.doi.org/10.1186/s12944-022-01718-7