Insights on Aggregation of Hen Egg-White Lysozyme from Raman Spectroscopy and MD Simulations

Protein misfolding and aggregation play a significant role in several neurodegenerative diseases. In the present work, the spontaneous aggregation of hen egg-white lysozyme (HEWL) in an alkaline pH 12.2 at an ambient temperature was studied to obtain molecular insights. The time-dependent changes in...

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Detalles Bibliográficos
Autores principales: Chalapathi, Divya, Kumar, Amrendra, Behera, Pratik, Sathi, Shijulal Nelson, Swaminathan, Rajaram, Narayana, Chandrabhas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609503/
https://www.ncbi.nlm.nih.gov/pubmed/36296716
http://dx.doi.org/10.3390/molecules27207122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609503/
https://www.ncbi.nlm.nih.gov/pubmed/36296716
http://dx.doi.org/10.3390/molecules27207122

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