Identification of Natural Compounds as Inhibitors of Pyruvate Kinase M2 for Cancer Treatment

The reliance of tumor cells on aerobic glycolysis is one of the emerging hallmarks of cancer. Pyruvate kinase M2 (PKM2), an important enzyme of glycolytic pathway, is highly expressed in a number of cancer cells. Tumor cells heavily depend on PKM2 to fulfill their divergent energetic and biosyntheti...

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Detalles Bibliográficos
Autores principales: Sarfraz, Iqra, Rasul, Azhar, Jabeen, Farhat, Sultana, Tayyaba, Adem, Şevki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609560/
https://www.ncbi.nlm.nih.gov/pubmed/36296707
http://dx.doi.org/10.3390/molecules27207113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609560/
https://www.ncbi.nlm.nih.gov/pubmed/36296707
http://dx.doi.org/10.3390/molecules27207113

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