Evaluating and Improving Neonatal Gentamicin Pharmacokinetic Models Using Aggregated Routine Clinical Care Data

Model-informed precision dosing (MIPD) can aid dose decision-making for drugs such as gentamicin that have high inter-individual variability, a narrow therapeutic window, and a high risk of exposure-related adverse events. However, MIPD in neonates is challenging due to their dynamic development and...

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Detalles Bibliográficos
Autores principales: Tong, Dominic M. H., Hughes, Jasmine H., Keizer, Ron J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609639/
https://www.ncbi.nlm.nih.gov/pubmed/36297524
http://dx.doi.org/10.3390/pharmaceutics14102089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609639/
https://www.ncbi.nlm.nih.gov/pubmed/36297524
http://dx.doi.org/10.3390/pharmaceutics14102089

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