Cargando…
Epilepsy-Induced High Affinity Blockade of the Cardiac Sodium Current I(Na) by Lamotrigine; A Potential for Acquired Arrythmias
Lamotrigine is widely prescribed to treat bipolar neurological disorder and epilepsy. It exerts its antiepileptic action by blocking voltage-gated sodium channels in neurons. Recently, the US Food and Drug Administration issued a warning on the use of Lamotrigine after observations of conduction ano...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609666/ https://www.ncbi.nlm.nih.gov/pubmed/36297320 http://dx.doi.org/10.3390/ph15101208 |