Serendipitous Discovery of a Competitive Inhibitor of FraB, a Salmonella Deglycase and Drug Target

Although salmonellosis, an infectious disease, is a significant global healthcare burden, there are no Salmonella-specific vaccines or therapeutics for humans. Motivated by our finding that FraB, a Salmonella deglycase responsible for fructose-asparagine catabolism, is a viable drug target, we initi...

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Detalles Bibliográficos
Autores principales: Thirugnanasambantham, Pankajavalli, Kovvali, Sravya, Cool, Austin, Gao, Yuan, Sabag-Daigle, Anice, Boulanger, Erin F., Mitton-Fry, Mark, Capua, Angela Di, Behrman, Edward J., Wysocki, Vicki H., Lindert, Steffen, Ahmer, Brian M. M., Gopalan, Venkat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609667/
https://www.ncbi.nlm.nih.gov/pubmed/36297159
http://dx.doi.org/10.3390/pathogens11101102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609667/
https://www.ncbi.nlm.nih.gov/pubmed/36297159
http://dx.doi.org/10.3390/pathogens11101102

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