Exploring Novel Pyridine Carboxamide Derivatives as Urease Inhibitors: Synthesis, Molecular Docking, Kinetic Studies and ADME Profile

The rapid development of resistance by ureolytic bacteria which are involved in various life-threatening conditions such as gastric and duodenal cancer has induced the need to develop a new line of therapy which has anti-urease activity. A series of pyridine carboxamide and carbothioamide derivative...

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Detalles Bibliográficos
Autores principales: Naseer, Ayesha, Osra, Faisal Abdulrhman, Awan, Asia Naz, Imran, Aqeel, Hameed, Abdul, Ali Shah, Syed Adnan, Iqbal, Jamshed, Zakaria, Zainul Amiruddin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609714/
https://www.ncbi.nlm.nih.gov/pubmed/36297400
http://dx.doi.org/10.3390/ph15101288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609714/
https://www.ncbi.nlm.nih.gov/pubmed/36297400
http://dx.doi.org/10.3390/ph15101288

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