Novel pH-Responsive Cubosome and Hexosome Lipid Nanocarriers of SN-38 Are Prospective for Cancer Therapy

HIGHLIGHTS: 1).. What are the main findings? Lipid nanoparticles containing novel synthetic aminolipids were formulated. Their internal nanostructures are sensitive to pH, being an inverse hexagonal phase at pH 7.4 and a bicontinuous cubic phase at pH 4.0–pH 7.0. Poorly soluble and highly potent ant...

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Detalles Bibliográficos
Autores principales: Rajesh, Sarigama, Zhai, Jiali, Drummond, Calum J., Tran, Nhiem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609773/
https://www.ncbi.nlm.nih.gov/pubmed/36297610
http://dx.doi.org/10.3390/pharmaceutics14102175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609773/
https://www.ncbi.nlm.nih.gov/pubmed/36297610
http://dx.doi.org/10.3390/pharmaceutics14102175

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