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Novel pH-Responsive Cubosome and Hexosome Lipid Nanocarriers of SN-38 Are Prospective for Cancer Therapy
HIGHLIGHTS: 1).. What are the main findings? Lipid nanoparticles containing novel synthetic aminolipids were formulated. Their internal nanostructures are sensitive to pH, being an inverse hexagonal phase at pH 7.4 and a bicontinuous cubic phase at pH 4.0–pH 7.0. Poorly soluble and highly potent ant...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609773/ https://www.ncbi.nlm.nih.gov/pubmed/36297610 http://dx.doi.org/10.3390/pharmaceutics14102175 |