Cargando…

Comparison of different methods to assess tacrolimus concentration intra-patient variability as potential marker of medication non-adherence

Background and objective: Non-adherence to tacrolimus commonly manifests as low drug concentrations and/or high intra-patient variability (IPV) of concentrations across multiple measurements. We aimed to compare several methods of tacrolimus IPV calculation and evaluate how well each reflects blood...

Descripción completa

Detalles Bibliográficos
Autores principales: Kostalova, Barbora, Mala-Ladova, Katerina, Sulkova, Sylvie Dusilova, Denhaerynck, Kris, De Geest, Sabina, Maly, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609782/
https://www.ncbi.nlm.nih.gov/pubmed/36313323
http://dx.doi.org/10.3389/fphar.2022.973564