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Gene Expression Analysis of Adapted Insect Cells during Influenza VLP Production Using RNA-Sequencing

Adaptive laboratory evolution has been used to improve production of influenza hemagglutinin (HA)-displaying virus-like particles (VLPs) in insect cells. However, little is known about the underlying biological mechanisms promoting higher HA-VLP expression in such adapted cell lines. In this article...

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Detalles Bibliográficos
Autores principales: Silvano, Marco, Correia, Ricardo, Virgolini, Nikolaus, Clarke, Colin, Alves, Paula M., Isidro, Inês A., Roldão, António
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609815/
https://www.ncbi.nlm.nih.gov/pubmed/36298794
http://dx.doi.org/10.3390/v14102238