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Gene Expression Analysis of Adapted Insect Cells during Influenza VLP Production Using RNA-Sequencing
Adaptive laboratory evolution has been used to improve production of influenza hemagglutinin (HA)-displaying virus-like particles (VLPs) in insect cells. However, little is known about the underlying biological mechanisms promoting higher HA-VLP expression in such adapted cell lines. In this article...
Autores principales: | Silvano, Marco, Correia, Ricardo, Virgolini, Nikolaus, Clarke, Colin, Alves, Paula M., Isidro, Inês A., Roldão, António |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609815/ https://www.ncbi.nlm.nih.gov/pubmed/36298794 http://dx.doi.org/10.3390/v14102238 |
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