Pharmacokinetic Herb-Drug Interactions of Glipizide with Andrographis paniculata (Burm. f.) and Andrographolide in Normal and Diabetic Rats by Validated HPLC Method

Co-administered medicinal herbs can modify a drug’s pharmacokinetics (PK), effectiveness, and toxicity. Andrographis paniculata (Burm. f.) ethanolic extract (APE) and andrographolide (AND) (a potent CYP2C9 inducer/inhibitor) can alter the pharmacokinetic parameters of glipizide (GLZ). This study aim...

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Detalles Bibliográficos
Autores principales: Sundhani, Elza, Nugroho, Agung Endro, Nurrochmad, Arief, Puspitasari, Ika, Amalia Prihati, Dita, Lukitaningsih, Endang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609824/
https://www.ncbi.nlm.nih.gov/pubmed/36296494
http://dx.doi.org/10.3390/molecules27206901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609824/
https://www.ncbi.nlm.nih.gov/pubmed/36296494
http://dx.doi.org/10.3390/molecules27206901

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