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Pharmacokinetic Herb-Drug Interactions of Glipizide with Andrographis paniculata (Burm. f.) and Andrographolide in Normal and Diabetic Rats by Validated HPLC Method

Co-administered medicinal herbs can modify a drug’s pharmacokinetics (PK), effectiveness, and toxicity. Andrographis paniculata (Burm. f.) ethanolic extract (APE) and andrographolide (AND) (a potent CYP2C9 inducer/inhibitor) can alter the pharmacokinetic parameters of glipizide (GLZ). This study aim...

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Detalles Bibliográficos
Autores principales:	Sundhani, Elza, Nugroho, Agung Endro, Nurrochmad, Arief, Puspitasari, Ika, Amalia Prihati, Dita, Lukitaningsih, Endang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609824/ https://www.ncbi.nlm.nih.gov/pubmed/36296494 http://dx.doi.org/10.3390/molecules27206901

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