The Effect of Biorelevant Hydrodynamic Conditions on Drug Dissolution from Extended-Release Tablets in the Dynamic Colon Model

The in vitro release of theophylline from an extended-release dosage form was studied under different hydrodynamic conditions in a United States Pharmacopoeial (USP) dissolution system II and a bespoke in vitro tubular model of the human colon, the Dynamic Colon Model (DCM). Five biorelevant motilit...

Descripción completa

Detalles Bibliográficos
Autores principales: O’Farrell, Connor, Simmons, Mark J. H., Batchelor, Hannah K., Stamatopoulos, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609852/
https://www.ncbi.nlm.nih.gov/pubmed/36297627
http://dx.doi.org/10.3390/pharmaceutics14102193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9609852/
https://www.ncbi.nlm.nih.gov/pubmed/36297627
http://dx.doi.org/10.3390/pharmaceutics14102193

Ejemplares similares